Psychotic and affective symptoms of early-onset bipolar disorder: an observational study of patients in first manic episode

Psychotic and affective symptoms of early-onset bipolar disorder: an observational study of patients in first manic episode

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Objective: Presence of psychotic symptoms seems to be a commonplace in early-onset bipolar disorder (BD).However, few studies have examined their occurrence in adolescent-onset BD.We sought to investigate the frequency of affective and psychotic symptoms observed during the first manic episode in adolescents.Methods: Forty-nine adolescents with bipolar I disorder incredibleindiatourtravels.com (DSM-IV criteria) were admitted to a psychiatric hospital during their first acute manic episode.Assessment for current psychiatric diagnosis was performed by direct clinical interview and the DSM-IV version of the Diagnostic Interview for Children and Adolescents (DICA).

Results: Teenage inpatients with BD consistently exhibited typical manic features, such as euphoria, grandiosity, and psychomotor agitation.In addition, disorganization and psychotic symptoms were present in 82 and 55% of the total sample, respectively.There was no significant difference in symptoms between early- and late-adolescent subgroups.Remarkably, most aptamil allerpro patients (76%) reported previous depressive episode(s); of these, 47% had prominent psychotic features in the prior depressive period.Conclusion: These findings suggest that disorganization and psychotic symptoms during the first manic episode are salient features in adolescent-onset BD, and that psychotic depression frequently may precede psychotic mania.

Nevertheless, differential diagnosis with schizophrenia should be routinely ruled out in cases of early-onset first psychotic episode.